Package: grantham 0.1.1

Ramiro Magno

grantham: Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Authors:Ramiro Magno [aut, cre], Isabel Duarte [aut], Ana-Teresa Maia [aut], CINTESIS [cph, fnd]

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grantham.pdf |grantham.html✨
grantham/json (API)
NEWS

# Install 'grantham' in R:
install.packages('grantham', repos = c('https://patterninstitute.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/maialab/grantham/issues

Datasets:

On CRAN:

2.78 score 4 stars 1 packages 7 scripts 234 downloads 9 exports 21 dependencies

Last updated 4 months agofrom:6768b1f580. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKOct 28 2024
R-4.5-winOKOct 28 2024
R-4.5-linuxOKOct 28 2024
R-4.4-winOKOct 28 2024
R-4.4-macOKOct 28 2024
R-4.3-winOKOct 28 2024
R-4.3-macOKOct 28 2024

Exports:%>%amino_acid_pairsamino_acidsas_one_letteras_three_lettergrantham_distancegrantham_distance_exactgrantham_distance_originalgrantham_equation

Dependencies:clicpp11dplyrfansigenericsgluelifecyclemagrittrpillarpkgconfigpurrrR6rlangstringistringrtibbletidyrtidyselectutf8vctrswithr